Professor Shôn Lewis MD, FMedSci

Photograph of Shôn Lewis

Professor of Adult Psychiatry

3.308 Jean McFarlane Building

University Place

Oxford Road

Manchester M13 9PL

Role

Professor of Adult Psychiatry, University of Manchester 1994-current

Director, Institute of Brain, Behaviour and Mental Health 2012-current

Honorary Consultant in Psychiatry, Manchester Mental Health and Social Care Trust

Associate Director, NIHR Mental Health Research Network 2004-2015

NIHR Senior Investigator and Senior Leader 2008-current

Member, Executive Greater Manchester CLRN 2009-2015

Academic Lead, Mental Health Domain, Manchester Academic HS Centre 2013-current

Trustee and Board Member, Rethink Mental Illness 2009-12

Research

Shôn Lewis's research interests focus on risk factors and new interventions in schizophrenia and psychosis, including the use of new technologies. He has published 5 books and 180 scientific articles, including 3 citation classics. He receives research funding from MRC, NIHR and EU.

 

Biography

Shôn Lewis has been Professor of Adult Psychiatry at the University of Manchester since 1994.  He trained clinically at the Maudsley Hospital. He has been Chair of the Royal College
of Psychiatrists’ research committee and served on the Wellcome Trust and the MRC Neurosciences and Mental Health Boards.

 

His research interests focus on risk factors and new interventions in schizophrenia and psychosis, including the use of new technologies. He has published 5 books and 180 scientific articles, including 3 citation classics. He receives research funding from MRC, NIHR and EU. He was elected in 2008 as a fellow of the Academy of Medical Sciences.  He has held an NIHR Senior Investigator award since 2008.

 

He works as an honorary consultant psychiatrist in Manchester Mental Health and Social Care Trust and was R&D Director 2004-8. He was a trustee and board member of the charity Rethink Mental Illness 2009-12 and was involved in setting up the Schizophrenia Commission. He is Associate Director of the NIHR CRN Mental Health and Neuroscience Division and is Director of the Institute of Brain, Behaviour and Mental Health at the University of Manchester.

Qualifications

BSc Psychol (1st Class)

MBBS

MRCPsych

MPhil

MD

F Med Sci

 

Publications

2016

  • Drake, R. J., Addington, J., Viswanathan, A. C., Lewis, S. W., Cotter, J., Yung, A. R., & Abel, K. M. (2016). How age and gender predict illness course in a first-episode nonaffective psychosis cohort. Journal of Clinical Psychiatry, 77(3), e283-e289. DOI:10.4088/JCP.14m09369
    . Publication link: 53b7438f-64cf-420e-9bd4-bfb06f9228b1

2015

  • Drake, R. J., Nordentoft, M., Haddock, G., Arango, C., Fleischhacker, W. W., Glenthøj, B., ... Glenthoj, B. (2015). Modeling determinants of medication attitudes and poor adherence in early nonaffective psychosis: implications for intervention.Schizophrenia bulletin, 41(3), [SZBLTN-INVART-14-0548.R2]. DOI:10.1093/schbul/sbv015
    . Publication link: ee33c1cf-4546-467e-a884-63f3e1045e35 | PubMed:25750247
  • Fond, G., d'Albis, M-A., Jamain, S., Tamouza, R., Arango, C., Fleischhacker, W. W., ... Leboyer, M. (2015). The promise of biological markers for treatment response in first-episode psychosis: a systematic review.Schizophrenia bulletin, 41(3). DOI:10.1093/schbul/sbv002
    . Publication link: a78f6c5e-fce8-4a2a-bbdd-58f57715937e | PubMed:25759473
  • Hayhurst, K. P., Drake, R. J., Massie, J. A., Dunn, G., & Lewis, S. W. (2015). Patients' subjective rating of mental health improvement in a randomised controlled trial.Psychiatry research, 229(1-2), 593-595. DOI:10.1016/j.psychres.2015.07.038
    . Publication link: d22a9ce4-4c55-4dfb-b2e3-615987589ff1 | PubMed:26208989
  • Lees, J., Applegate, E., Emsley, R., Lewis, S., Michalopoulou, P., Collier, T., ... Collier, T. (2015). Calibration and cross-validation of MCCB and CogState in schizophrenia.Psychopharmacology, 232(21-22). DOI:10.1007/s00213-015-3960-8
    . Publication link: 9e837f6b-189a-48c6-a6bf-d8a9673c90ec | PubMed:26018529
  • Leucht, S., Winter-van Rossum, I., Heres, S., Arango, C., Fleischhacker, W. W., Glenthøj, B., ... Sommer, I. E. (2015). The optimization of treatment and management of schizophrenia in Europe (OPTiMiSE) trial: rationale for its methodology and a review of the effectiveness of switching antipsychotics.Schizophrenia bulletin, 41(3). DOI:10.1093/schbul/sbv019
    . Publication link: 875f365d-4547-48d6-b8ab-b80732aac9d8 | PubMed:25786408
  • Morrison, A. P., Shryane, N., Fowler, D., Birchwood, M., Gumley, A. I., Taylor, H. E., ... Bentall, R. P. (2015). Negative cognition, affect, metacognition and dimensions of paranoia in people at ultra-high risk of psychosis: A multi-level modelling analysis. Psychological Medicine, 45(12), 2675-2684. DOI:10.1017/s0033291715000689
    . Publication link: 53b249f0-95f2-4db7-b6fa-b03267aa439c
  • Whelan, P., Machin, M., Lewis, S., Buchan, I., Sanders, C., Applegate, E., ... Ainsworth, J. (2015). Mobile early detection and connected intervention to coproduce better care in severe mental illness.Studies in health technology and informatics, 216.
    . Publication link: d98b403a-2196-4f0b-a4fd-6708bfa02e64 | PubMed:26262023
  • Wykes, T., Haro, J. M., Belli, S. R., Obradors-Tarragó, C., Arango, C., Ayuso-Mateos, J. L., ... Wittchen, H-U. (2015). Mental health research priorities for Europe.The lancet. Psychiatry, 2(11). DOI:10.1016/S2215-0366(15)00332-6
    . Publication link: 1bca2351-6900-4c4b-ae06-432118e857dc | PubMed:26404415

2014

  • Birchwood, M., Michail, M., Meaden, A., Tarrier, N., Lewis, S., Wykes, T., ... Peters, E. (2014). Cognitive behaviour therapy to prevent harmful compliance with command hallucinations (COMMAND): A randomised controlled trial. The Lancet Psychiatry, 1(1), 23-33.
    . Publication link: 818e2cfc-5319-4d8c-89bf-3039c5999a36
  • Haro, J. M., Ayuso-Mateos, J. L., Bitter, I., Demotes-Mainard, J., Leboyer, M., Lewis, S. W., ... Walker-Tilley, T. (2014). ROAMER: roadmap for mental health research in Europe.International Journal of Methods in Psychiatric Research, 23 Suppl 1(1), 1-14. DOI:10.1002/mpr.1406
    . Publication link: a0650ad7-b2e8-4369-8439-dcbe8a036066 | PubMed:24375532
  • Hartley, S., Varese, F., Vasconcelos e Sa, D., Udachina, A., Barrowclough, C., Bentall, R. P., ... Palmier-Claus, J. (2014). Compliance in experience sampling methodology: The role of demographic and clinical characteristics. Psychosis, 6(1), 70-73. DOI:10.1080/17522439.2012.752520
    . Publication link: a7ce366b-ff20-49db-966e-362a57bb03d2
  • Hayhurst, K. P., Drake, R. J., Massie, J. A., Dunn, G., Barnes, T. R. E., Jones, P. B., & Lewis, S. W. (2014). Improved quality of life over one year is associated with improved adherence in patients with schizophrenia. European Psychiatry, 29(3), 191-196. DOI:10.1016/j.eurpsy.2013.03.002
    . Publication link: a91e4a5f-eb28-4505-97d9-a0df75062fa5 | PubMed:23769325
  • Hayhurst, K. P., Drake, R. J., Massie, J. A., Dunn, G., Lewis, S. W., Massie, J. A., & Lewis, S. W. (2014). Validity of subjective versus objective quality of life assessment in people with schizophrenia. B M C Psychiatry, 14(1), 365. DOI:10.1186/s12888-014-0365-x
    . Publication link: a19cadc4-acf7-4659-be85-819d0dd77003 | PubMed:25539658
  • Palmier-Claus, J. E., Taylor, P. J., Ainsworth, J., Machin, M., Dunn, G., & Lewis, S. W. (2014). The temporal association between self-injurious thoughts and psychotic symptoms: a mobile phone assessment study.Suicide & life-threatening behavior, 44(1), 101-110. DOI:10.1111/sltb.12064
    . Publication link: 006866b1-54a3-4607-b58e-1560fcc80394 | PubMed:24261643
  • Schumann, G., Binder, E. B., Holte, A., de Kloet, E. R., Oedegaard, K. J., Robbins, T. W., ... Wittchen, H. U. (2014). Stratified medicine for mental disorders.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 24(1), 5-50. DOI:10.1016/j.euroneuro.2013.09.010
    . Publication link: 731288ef-f98e-4402-95e5-62a176c5afdd | PubMed:24176673
  • van der Feltz-Cornelis, C. M., van Os, J., Knappe, S., Schumann, G., Vieta, E., Wittchen, H-U., ... Haro, J. M. (2014). Towards Horizon 2020: challenges and advances for clinical mental health research - outcome of an expert survey.Neuropsychiatric disease and treatment, 10, 1057-1068. DOI:10.2147/NDT.S59958
    . Publication link: f5022c35-8ee6-449a-812a-7fe0d2971755 | PubMed:25061300

2013

  • Ainsworth, J., Palmier-Claus, J. E., Machin, M., Barrowclough, C., Dunn, G., Rogers, A., ... Lewis, S. (2013). A comparison of two delivery modalities of a mobile phone-based assessment for serious mental illness: native smartphone application vs text-messaging only implementations.Journal of medical Internet research, 15(4). DOI:10.2196/jmir.2328
    . Publication link: dd489a77-5c17-457b-b7bc-5aeb2b1dd296 | PubMed:23563184
  • Barnes, T. R. E., Drake, R. J., Dunn, G., Hayhurst, K. P., Jones, P. B., & Lewis, S. W. (2013). Effect of prior treatment with antipsychotic long-acting injection on randomised clinical trial treatment outcomes. British Journal of Psychiatry, 203(3), 215-220. DOI:10.1192/bjp.bp.113.125807
    . Publication link: 82c1e296-067a-474a-8153-68148cd58733 | PubMed:23888001
  • Birchwood, M., Connor, C., Lester, H., Patterson, P., Freemantle, N., Marshall, M., ... Singh, S. P. (2013). Reducing duration of untreated psychosis: care pathways to early intervention in psychosis services.The British journal of psychiatry : the journal of mental science, 203(1), 58-64. DOI:10.1192/bjp.bp.112.125500
    . Publication link: 7102fb8b-3078-4689-b3c3-236f4250b50e | PubMed:23703317
  • Lewis, S., Zammit, S., Kounali, D., Cannon, M., David, A. S., Gunnell, D., ... Lewis, G. (2013). Psychotic experiences and psychotic disorders at age 18 in relation to psychotic experiences at age 12 in a longitudinal population-based cohort study.The American journal of psychiatry, 170(7), 742-750. DOI:10.1176/appi.ajp.2013.12060768
    . Publication link: 7d3b487a-f61a-44c0-a03a-c7627682ba57 | PubMed:23639948
  • Michalopoulou, P. G., Lewis, S. W., Wykes, T., Jaeger, J., & Kapur, S. (2013). Treating impaired cognition in schizophrenia: The case for combining cognitive-enhancing drugs with cognitive remediation. European Neuropsychopharmacology, 23(8), 790-798. DOI:10.1016/j.euroneuro.2013.03.012
    . Publication link: 8cf3d457-7e7e-496c-ac36-f01be8842810 | PubMed:23619163
  • Palmier-Claus, J. E., Ainsworth, J., Machin, M., Dunn, G., Barkus, E., Barrowclough, C., ... Lewis, S. W. (2013). Affective Instability Prior to and after Thoughts about Self-Injury in Individuals With and At-Risk of Psychosis: A Mobile Phone Based Study. Archives of Suicide Research, 17(3), 275-287. DOI:10.1080/13811118.2013.805647
    . Publication link: 7d27c1b4-1c69-44a2-b36e-0b12c878dbc7 | PubMed:23889576
  • Palmier-Claus, J. E., Dunn, G., Taylor, H., Morrison, A. P., & Lewis, S. W. (2013). Cognitive-self consciousness and metacognitive beliefs: Stress sensitization in individuals at ultra-high risk of developing psychosis. British Journal of Clinical Psychology, 52(1), 26-41. DOI:10.1111/j.2044-8260.2012.02043.x
    . Publication link: 9153bd5d-8aac-47b9-bcd3-0f2db5012e4a | PubMed:23398110
  • Palmier-Claus, J. E., Rogers, A., Ainsworth, J., Machin, M., Barrowclough, C., Laverty, L., ... Lewis, S. W. (2013). Integrating mobile-phone based assessment for psychosis into people's everyday lives and clinical care: A qualitative study. BMC Psychiatry, 13, [34]. DOI:10.1186/1471-244X-13-34
    . Publication link: 35704376-c30e-437e-b811-d249700a5c34 | PubMed:23343329
  • Peluso, M. J., Lewis, S. W., Barnes, T. R. E., & Jones, P. B. (2013). Non-neurological and metabolic side effects in the Cost Utility of the Latest Antipsychotics in Schizophrenia Randomised Controlled Trial (CUtLASS-1). Schizophrenia Research, 144(1-3), 80-86. DOI:10.1016/j.schres.2012.12.008
    . Publication link: 7eb7912b-a369-4a12-b55b-98dea90426ee | PubMed:23313462
  • Winsper, C., Singh, S. P., Marwaha, S., Amos, T., Lester, H., Everard, L., ... Birchwood, M. (2013). Pathways to violent behavior during first-episode psychosis: A report from the UK national EDEN study. JAMA Psychiatry, 70(12), 1287-1293. DOI:10.1001/jamapsychiatry.2013.2445
    . Publication link: d364e46e-3567-46eb-8fc4-a63ae59c30de | PubMed:24089149

2012

2011

  • Barkus, E., Smallman, R., Royle, N., Barkus, C., Lewis, S., & Rushe, T. (2011). Auditory false perceptions are mediated by psychosis risk factors. Cognitive Neuropsychiatry, 16(4), 289-302. DOI:10.1080/13546805.2010.530472
    . Publication link: 0d519995-b5ca-45e1-84ae-c997a09c14ec
  • Birchwood, M., Peters, E., Tarrier, N., Dunn, G., Lewis, S., Wykes, T., ... Michail, M. (2011). A multi-centre, randomised controlled trial of cognitive therapy to prevent harmful compliance with command hallucinations. BMC Psychiatry, 11, [155]. DOI:10.1186/1471-244X-11-155
    . Publication link: c1f45f4b-f1ca-4ddf-bbd1-9f5a9d246c80
  • Lewis, S. W., Morrison, A., French, P., Stewart, S., Birchwood, M., Fowler, D., ... Dunn, G. (2011). Early detection and intervention evaluation for people at high-risk of psychosis (EDIE-2): A multisite randomised controlled trial of cognitive therapy for at risk mental states.Archives of General Psychiatry.
    . Publication link: 8dba6ba2-28cc-44b9-b095-0eb0ee3032d4
  • Morrison, A. P., Stewart, S. L. K., French, P., Bentall, R. P., Birchwood, M., Byrne, R., ... Dunn, G. (2011). Early detection and intervention evaluation for people at high-risk of psychosis-2 (EDIE-2): Trial rationale, design and baseline characteristics. Early Intervention in Psychiatry, 5(1), 24-32. DOI:10.1111/j.1751-7893.2010.00254.x
    . Publication link: c17eca70-94c5-45ba-8472-099fe7ac36d4 | PubMed:21272272
  • Palmier-Claus, J. E., Dunn, G., Morrison, A. P., & Lewis, S. W. (2011). The role of metacognitive beliefs in stress sensitisation, self-esteem variability, and the generation of paranoia. Cognitive Neuropsychiatry, 16(6), 530-546. DOI:10.1080/13546805.2011.561583
    . Publication link: f1b0bf91-ba8f-494f-9c96-ee2db64dd00d | PubMed:22098083
  • Palmier-Claus, J. E., Myin-Germeys, I., Barkus, E., Bentley, L., Udachina, A., Delespaul, P. A. E. G., ... Dunn, G. (2011). Experience sampling research in individuals with mental illness: Reflections and guidance. Acta Psychiatrica Scandinavica, 123(1), 12-20. DOI:10.1111/j.1600-0447.2010.01596.x
    . Publication link: 3217f829-8d83-498a-ab35-fcaf063fd95b
  • Palmier-Claus, J., Dunn, G., Drake, R., & Lewis, S. (2011). The negative and positive self: A longitudinal study examining self-esteem, paranoia and negative symptoms in individuals with first-episode psychosis. Early Intervention in Psychiatry, 5(2), 150-155. DOI:10.1111/j.1751-7893.2010.00250.x
    . Publication link: 75b50ae4-0377-4cf1-ab81-8b1bfb7fa49b

2010

  • Barrowclough, C., Haddock, G., Wykes, T., Beardmore, R., Conrod, P., Craig, T., ... Tarrier, N. (2010). Integrated motivational interviewing and cognitive behavioural therapyfor people with psychosis and comorbid substance misuse: Randomised controlled trial. BMJ, 341(7784), 1204. [c6325]. DOI:10.1136/bmj.c6325
    . Publication link: e774d278-f9d9-4f20-a7aa-062207d1df94 | PubMed:21106618
  • Drake, R. J., & Lewis, S. W. (2010). Valuing prodromal psychosis: What do we get and what is the price?. Schizophrenia Research, 120(1-3), 38-41. DOI:10.1016/j.schres.2010.03.013
    . Publication link: 247f83e7-976b-4462-be26-54d26ffd9546 | PubMed:20417060
  • Geddes, J. R., Goodwin, G. M., Rendell, J., Morriss, R., Alder, N., Juszczak, E., ... Sachs, G. (2010). Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar i disorder (BALANCE): A randomised open-label trial. The Lancet, 375(9712), 385-395. DOI:10.1016/S0140-6736(09)61828-6
    . Publication link: 3eb0b28d-fece-4662-a05a-f482d69de6e3
  • Hayhurst, K. P., Drake, R. J., & Lewis, S. W. (2010). Patient factors associated with receipt of combination antipsychotic drug therapy in the treatment of schizophrenia. Journal of Psychopharmacology, 24(1), 83-89. DOI:10.1177/0269881108095169
    . Publication link: 0f864229-9cb9-47e2-8e3a-e8f6dde6f159 | PubMed:18719041
  • McGorry, P., Johanessen, J. O., Lewis, S., Birchwood, M., Malla, A., Nordentoft, M., ... Yung, A. (2010). Early intervention in psychosis: Keeping faith with evidence-based health care. Psychological Medicine, 40(3), 399-404. DOI:10.1017/S0033291709991346
    . Publication link: ed3d19b7-fee9-4f38-8278-826fa58a503d
  • Ruhrmann, S., Schultze-Lutter, F., Salokangas, R. K. R., Heinimaa, M., Linszen, D., Dingemans, P., ... Klosterkötter, J. (2010). Prediction of psychosis in adolescents and young adults at high risk: Results from the prospective European prediction of psychosis study. Archives of General Psychiatry, 67(3), 241-251. DOI:10.1001/archgenpsychiatry.2009.206
    . Publication link: 85addc4e-74e3-42cc-a3f1-a52a27212346

2009

  • Haddock, G., Cross, Z., Beardmore, R., Tarrier, N., Lewis, S., Moring, J., & Barrowclough, C. (2009). Assessing illicit substance use in schizophrenia: The relationship between self report and detection by hair analysis. Schizophrenia Research, 114(1-3), 180-181. DOI:10.1016/j.schres.2009.07.020
    . Publication link: 5a3e8f4e-ebcb-4dac-8b6c-c91cbcb02ba5

2008

  • Davies, L., Davies, L. M., Barnes, T. R. E., Jones, P. B., Lewis, S., Gaughran, F., ... Lloyd, H. (2008). A randomized controlled trial of the cost-utility of second-generation antipsychotics in people with psychosis and eligible for clozapine. Value in Health, 11(4), 549-562. DOI:10.1111/j.1524-4733.2007.00280.x
    . Publication link: faf2c3c8-9217-42f3-8480-ef34bbf69828

2007

  • Bentall, R. P., Fernyhough, C., Morrison, A. P., Lewis, S., & Corcoran, R. (2007). Prospects for a cognitive-developmental account of psychotic experiences. British Journal of Clinical Psychology, 46(2), 155-173. DOI:10.1348/014466506X123011
    . Publication link: b6f1c227-fec1-4141-a298-eecd835b4cac
  • Davies, L. M., Lewis, S., Jones, P. B., Barnes, T. R. E., Gaughran, F., Hayhurst, K., ... Lloyd, H. (2007). Cost-effectiveness of first- v. second-generation antipsychotic drugs: Results from a randomised controlled trial in schizophrenia responding poorly to previous therapy. British Journal of Psychiatry, 191(JULY), 14-22. DOI:10.1192/bjp.bp.106.028654
    . Publication link: 5f57f967-10ef-4c8a-915d-ad3c922ff704
  • Drake, R. J., Dunn, G., Tarrier, N., Bentall, R. P., Haddock, G., & Lewis, S. W. (2007). Insight as a predictor of the outcome of first-episode nonaffective psychosis in a prospective cohort study in England. Journal of Clinical Psychiatry, 68(1), 81-86.
    . Publication link: 277f7b60-6d32-4986-b135-00ba0adc6569
  • Drake, R., Haddock, G., Tarrier, N., Bentall, R., & Lewis, S. (2007). The Psychotic Symptom Rating Scales (PSYRATS): Their usefulness and properties in first episode psychosis. Schizophrenia Research, 89(1-3), 119-122. DOI:10.1016/j.schres.2006.04.024
    . Publication link: 16ae7813-7782-45d0-a120-c2af7ce0023f
  • French, P., Shryane, N., Bentall, R. P., Lewis, S. W., & Morrison, A. P. (2007). Effects of cognitive therapy on the longitudinal development of psychotic experiences in people at high risk of developing psychosis. British Journal of Psychiatry, 191(51), s82-s87. DOI:10.1192/bjp.191.51.s82
    . Publication link: 3c4b833f-e7bb-427e-9f9c-8145921c50bb
  • Morrison, A. P., French, P., Parker, S., Roberts, M., Stevens, H., Bentall, R. P., & Lewis, S. W. (2007). Three-year follow-up of a randomized controlled trial of cognitive therapy for the prevention of psychosis in people at ultrahigh risk. Schizophrenia Bulletin, 33(3), 682-687. DOI:10.1093/schbul/sbl042
    . Publication link: 181cb79e-1541-4737-8079-d96864d51e7a
  • Jones, P. B., Barnes, T. R. E., Elton, P., Davies, L., Dunn, G., Lloyd, H., ... Lewis, S. (2007). First- vs second-generation antipsychotic drugs in schizophrenia: Reply [4]. Archives of General Psychiatry, 64(8), 979-980. DOI:10.1001/archpsyc.64.8.979
    . Publication link: a46d9ca5-4a8b-4d7f-941a-6bf76d82f2cb

2006

  • Barkus, E., Stirling, J., Hopkins, R., & Lewis, S. (2006). The presence of neurological soft signs along the psychosis proneness continuum. Schizophrenia Bulletin, 32(3), 573-577. DOI:10.1093/schbul/sbj037
    . Publication link: 9d50b4c0-6e39-4189-a457-03d28525d839
  • Haddock, G., Lewis, S., Bentall, R., Dunn, G., Drake, R., & Tarrier, N. (2006). Influence of age on outcome of psychological treatments in first-episode psychosis. British Journal of Psychiatry, 188, 250-254. DOI:10.1192/bjp.188.3.250
    . Publication link: df490138-a1a8-4049-b5f6-5709f5e6feb9 | PubMed:16507967
  • Lewis, S. W., Davies, L., Jones, P. B., Barnes, T. R. E., Murray, R. M., Kerwin, R., ... Dunn, G. (2006). Randomised controlled trials of conventional antipsychotic versus new atypical drugs, and new atypical drugs versus clozapine, in people with schizophrenia responding poorly to, or intolerant of, current drug treatment. Health Technology Assessment, 10(17), 1-94.
    . Publication link: 55da2b43-eb8c-47c2-b97d-8e9542613068 | PubMed:16707074
  • Lewis, S. W., Davies, L., Jones, P. B., Barnes, T. R. E., Murray, R. M., Kerwin, R., ... Dunn, G. (2006). Randomised controlled trials of conventional antipsychotic versus new atypical drugs, and new atypical drugs versus clozapine, in people with schizophrenia responding poorly to, or intolerant of, current drug treatment. Health Technology Assessment, 10(17), 1-94. DOI:10.3310/hta10170
    . Publication link: fc017613-6491-4516-b711-759aaf9ab25c
  • Tarrier, N., Haddock, G., Lewis, S., Drake, R., & Gregg, L. (2006). Suicide behaviour over 18 months in recent onset schizophrenic patients: The effects of CBT. Schizophrenia Research, 83(1), 15-27. DOI:10.1016/j.schres.2005.12.846
    . Publication link: 35c3149f-8924-4012-85d1-c4f20bef9633

2005

2004

  • Tarrier, N., Lewis, S., Haddock, G., Bentall, R., Drake, R., Kinderman, P., ... Dunn, G. (2004). Cognitive-behavioural therapy in first-episode and early schizophrenia: 18-month follow-up of a randomised controlled trial. British Journal of Psychiatry, 184, 231-239. DOI:10.1192/bjp.184.3.231
    . Publication link: a58a9fdb-2716-444c-8c38-07deafa6f9cb

2003

  • Drake, R. J., & Lewis, S. W. (2003). Insight and neurocognition in schizophrenia. Schizophrenia Research, 62(1-2), 165-173. DOI:10.1016/S0920-9964(02)00382-1
    . Publication link: 5d924336-40bd-40b9-8b70-bf252ae99c5f
  • Drake, R., Lewis, S. W., Haley, C. J., & Benatall, R. P. (2003). Health beliefs link to duration of untreated psychosis and attitudes to late treatment in early psychosis.Social Psychiatry and Psychiatric Epidemiology, 38(6).
    . Publication link: 71d9d6e6-d94b-441d-a44e-a041ad3d42a2
  • Hayhurst, K. P., Brown, P., & Lewis, S. W. (2003). Postcode prescribing for schizophrenia. British Journal of Psychiatry, 182, 281-283. DOI:10.1192/bjp.182.4.281
    . Publication link: 6ea4c4e1-d98b-4bb5-b374-60975a09b4b3
  • Lewis, S. W., & Drake, R. J. (2003). More than one dimension of insight in a first episode follow-up study of non-affective psychosis.Schizophrenia Research, 60(1).
    . Publication link: 8bcd9b49-ed80-420a-9234-71d1cfec3ef9
  • Lewis, S. W., & Hopkins, R. S. (2003). Negative priming in first episode psychosis.Schizophrenia Research, 60(1).
    . Publication link: ad799965-13a7-4c52-8dc3-2442f45ea540
  • Lewis, S. W., Barkus, E. J., Stirling, J., & Hopkins, R. (2003). The profile of schizotypy in a normal (student) population.Schizophrenia Research, 60(1).
    . Publication link: b9ecc93d-446f-47dd-8fb4-f114411c91d5
  • Lewis, S. W., Bentall, R. P., Tarrier, G., Haddock, R., Drake, R., & Day, J. (2003). Relationships matter: the impact of the therapeutic alliance on outcome in schizophrenia.Schizophrenia Research, 60(1).
    . Publication link: 9671f6c4-c8a6-4e54-a529-c2f0fe191571
  • Lewis, S. W., Massie, J., Marwick, A., Sowden, E., & Mahmood, A. (2003). Psychopathological influences on self-rated and external assessments of quality of life in schizophrenia.Schizophrenia Research, 60(1).
    . Publication link: d27619bb-859a-4c06-b0b0-0441320053e7
  • Lewis, S. W., Morrison, A. P., Bentall, R. P., French, P., Kilcommons, A., Green, J., & Walford, L. (2003). Cognitive therapy in ultra high risk individuals for psychosis: randomized controlled trial.Schizophrenia Research, 60(1).
    . Publication link: fdc3eb6c-739e-4ade-8310-870a8f1b9d8f
  • Lewis, S. W., Stirling, J., White, C., Hopkins, R., Huddy, A., & Montague, L. (2003). Neurological soft signs (NSSS) in first episode psychosis predict ten year outcome. Schizophrenia Research, 60(1).
    . Publication link: cc8616e6-01d9-45ba-9e45-8b9e4eb93d4e
  • Stirling, J., White, C., Lewis, S., Hopkins, R., Tantam, D., Huddy, A., & Montague, L. (2003). Neurocognitive function and outcome in first-episode schizophrenia: A 10-year follow-up of an epidemiological cohort. Schizophrenia Research, 65(2-3), 75-86. DOI:10.1016/S0920-9964(03)00014-8
    . Publication link: 477ce143-d6c2-40b8-b36b-eedd61dea728

2002

  • Guerra, A., Fearon, P., Sham, P., Jones, P., Lewis, S., Mata, I., & Murray, R. (2002). The relationship between predisposing factors, premorbid function and symptom dimensions in psychosis: An integrated approach. European Psychiatry, 17(6), 311-320.
    . Publication link: 96c7ffe0-8ca1-4a0a-9c5e-c90b3fde0f9d
  • Hayhurst, K., Brown, P., & Lewis, S. W. (2002). The cost-effectiveness of clozapine: A controlled, population-based, mirror-image study. Journal of Psychopharmacology, 16(2), 169-175. DOI:10.1177/026988110201600208
    . Publication link: c0296aa7-8bf5-4c0f-8a97-a9124e280fab
  • Lewis, S. (2002). The European first-episode schizophrenia network. British Journal of Psychiatry, 181(43), -s2.
    . Publication link: 72937881-0179-4e38-b82e-ffbb9dd423f7
  • Lewis, S. W., & Drake, R. (2002). Neurocognitive predictors of poor insight in early schizophrenia. Schizophrenia Research, 53(3).
    . Publication link: 82a2f1b4-848a-4e7a-9371-63eadd463ee3
  • Lewis, S. W., & Drake, R. (2002). Treatment of first episode and prodromal signs. Psychiatry, 1(10).
    . Publication link: 2f05927b-94c1-45cb-94cb-d4a95ab936a1
  • Lewis, S. W., Drake, R., & Tarrier, N. (2002). Predictors of medium-term outcome from first-episode schizophrenia. Schizophrenia Research.
    . Publication link: ff793d04-088a-4182-85e2-9297166de947
  • Lewis, S. W., Haley, C. J., Drake, R., & Benatall, R. (2002). Class of drug treatment does not affect drug attitudes in early schizophrenia. Schizophrenia Research, 53(3).
    . Publication link: 1b6231b4-1136-4497-8a4c-9a434f46c07b
  • Lewis, S. W., Hopkins, R. S., White, C. J., Stirling, J., Morris, J., & Montague, L. (2002). Deaths in a first episode psychosis cohort in the 12 years after onset.Schizophrenia Research, 53(3).
    . Publication link: 46f262e0-db42-4984-9635-0e69a79fc776
  • Lewis, S. W., Morrison, A., Bentall, R., French, P., & Kilcommons, A. (2002). Very early intervention in prodromal psychosis: A randomised trial. Schizophrenia Research, 53(3).
    . Publication link: e7cfb2ca-9975-461d-8764-66ad9055ba6a
  • Lewis, S. W., Morrison, A., Bentall, R., French, P., Walford, L., & Kilcommons, A. (2002). A randomised controlled trial of early detection and cognitive therapy in individuals at risk of psychosis.British Journal of Psychotherapy, 181(43).
    . Publication link: e0caf017-9cd7-44de-8bd4-c13d6d91284c
  • Lewis, S. W., Morrison, A., Bentall, R., French, P., Walford, L., & Kilcommons, A. (2002). A randomised controlled trial of early detection and cognitive therapy in individuals of psychosis. Study design and interim analyses.British Journal of Psychiatry, 181supp 43.
    . Publication link: c62ccd71-689b-4bc6-9b63-207ba12ae85d
  • Lewis, S. W., Stirling, J., White, C., Hopkins, R., Huddy, A., & Montague, L. (2002). Onset predictors of clinical and functional outcome in individuals first diagnosed with a schizophrenic disorder 10-12 years ago. Schizophrenia Research, 53(3).
    . Publication link: df5eb753-828d-4e42-844b-1b6e2a2b5c0e
  • Lewis, S. W., White, C. J., Hopkins, R. S., Stirling, J., Morris, J., & Montague, L. (2002). Non-natural deaths and duration of untreated psychosis (DUP) in a first-episode psychosis cohort. Schizophrenia Research, 53(3).
    . Publication link: 8341f435-2027-462d-9eb7-99d79b671358
  • Lewis, S., Tarrier, N., Haddock, G., Bentall, R., Kinderman, P., Kingdon, D., ... Dunn, G. (2002). Randomised controlled trial of cognitive-behavioural therapy in early schizophrenia: Acute-phase outcomes. British Journal of Psychiatry, 181(43), s91-s97. DOI:10.1192/bjp.181.43.s91
    . Publication link: dcc71d6f-a11e-4e70-85fd-77e4ec745064
  • Morrison, A. P., Bentall, R. P., French, P., Walford, L., Kilcommons, A., Knight, A., ... Lewis, S. W. (2002). Randomised controlled trial of early detection and cognitive therapy for preventing transition to psychosis in high-risk individuals. Study design and interim analysis of transition rate and psychological risk factors. British Journal of Psychiatry, 181(43), s78-s84.
    . Publication link: cff46b60-b4a9-4117-ac17-f375af9d17c7
  • Guthrie, E. A., & Lewis, S. W. (2002). Modern Psychiatry for Student Doctors. Churchill Livingstone.
    . Publication link: 90252f68-f7c9-4b31-848e-95697318998d
  • Lewis, S. W., & Buchanan, R. W. (2002). Schizophrenia. Oxford University Press.
    . Publication link: 31c3f16e-3d37-442b-a9e4-648c3fd8e513
  • Lewis, S. W., Hughes, R., Turner, S., & Taylor, D. (2002). Delirium.In Neurological Emergencies. (Vol. 3)
    . Publication link: 69fe7e42-3e5b-44c0-b0cf-da6809cfb9d7

2001

2000

  • Lewis, S. W., Drake, R., Haley, C. J., & Akhtar, S. (2000). Causes and consequences of duration of untreated psychosis in first episode schizophrenia. British Journal of Psychiatry, 177.
    . Publication link: 70205359-03b1-4649-8bfe-99d127b0f9d1

1999

  • Haddock, G., Lewis, S., Barrowclough, C., & Tarrier, N. (1999). Hair analysis for substance use [7]. British Journal of Psychiatry, 174, 370.
    . Publication link: 1ea704d4-9efe-452b-95dc-fd45ffc6598b
  • Tarrier, N., Lewis, S. W., Barrowclough, C., Sellwood, W., Quinn, J., & Mainwaring, J. (1999). A randomised controlled effectiveness trial of a needs based psychosocial intervention service for carers of schizophrenic patients. British Journal of Psychiatry, 174, 506-511.
    . Publication link: d7125dfb-bc97-4dab-aa33-fe98ba3cbfa3

1998

  • Haddock, G., Morrison, A. P., Hopkins, R., Lewis, S., & Tarrier, N. (1998). Individual cognitive-behavioural interventions in early psychosis. British Journal of Psychiatry, 172(33), 101-106.
    . Publication link: ec127f8c-d7ab-4bb0-804b-c565231f54a3