Professor Louis Appleby

Photograph of Louis Appleby

Professor of Psychiatry

Centre for Mental Health and Safety
Institute for Brain, Behaviour and Mental Health
Jean McFarlane Building
The University of Manchester
Oxford Road
M13 9PL


Professor of Psychiatry at the University of Manchester and Director of the National Confidential Inquiry into Suicide and Homicide by People with Mental Illness.  He leads the National Suicide Prevention Strategy for England and is a Non-Executive Director of the Care Quality Commission, the NHS regulator.


Louis Appleby graduated in medicine in Edinburgh and subsequently trained in hospital medicine and psychiatry, the latter at the Institute of Psychiatry, London. He has an MD from Edinburgh and is a Fellow of the Royal Colleges of both Physicians and Psychiatrists. He has held research grants totalling £15.5m from the Wellcome Trust, MRC, Department of Health and other NHS sources.

Louis leads the Centre for Mental Health and Safety, investigating suicide and self-harm, violence and forensic services, the largest research unit in this field internationally.  Its findings have been the basis of Government policy on suicide prevention and are widely quoted by governments, professionals and charities.  From 2000-2010 Louis was seconded (part-time) as the Government's National Director for Mental Health to lead a national programme of reform in mental health care in England and from 2010-2014 he was National Clinical Director for Health and Criminal Justice.

Selected publications


  • Webb, R. T., Abel, K. M., Pickles, A., Appleby, L., King-Hele, S. A., & Mortensen, P. B. (2006). Mortality risk among offspring of psychiatric inpatients: A population-based follow-up to early adulthood. American Journal of Psychiatry, 163(12), 2170-2177. DOI:10.1176/appi.ajp.163.12.2170. Publication link: 155bfdf8-8ebc-47b8-802f-cf956e5de096 | PubMed:17151170


  • Appleby, L., Cooper, J., Hawton, K., Townsend, E., Deeks, J., Gunnell, D., & Bennewith, O. (2001). Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: before and after study. BMJ, 322 (7296), 1203-1207. DOI:10.1136/bmj.322.7296.1203. Publication link: 37b6efd9-9f0f-4f65-b794-8b9d712b0d57

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Research projects