Professor Bill Deakin PhD, FRCPsych, FmedSci

Photograph of Bill Deakin

Professor of Psychiatry and Director NPU

Neuroscience and Psychiatry Unit
G.907 Stopford Building

Research

Bill Deakin heads Neuroscience Research in the Division of Psychiatry. An important focus of his group is to use modern imaging techniques to directly visualise 5HT and glutamate working in the brain. Patients and volunteers lie in a magnetic resonance imaging scanner and the images show which parts of the brain respond to drugs chosen to probe 5HT or glutamate functioning and how it performs mental tasks. The group can show, for example, that a single dose of an antidepressant drug lights up areas of the brain concerned with anxiety responses and turns off other areas concerned with memory in healthy volunteers.

The group can also visualise how these neurotransmitters modify how the brain processes information. For example, viewing the image of a fearful face engaged regions of the brain concerned with emotion; a pre-dose of an antidepressant specifically affects this part of the response while not affecting fear responses in other brain regions. They are now investigating these effects in patients with anxiety, depression and antisocial behaviour.

Humans share the same set of about 30,000 genes including those concerned with 5HT and glutamate, but the particular copies we each carry from our mother and father are often slightly different and vary in their activity. Comparing brain responses in individuals with different variants is a new focus of the group’s work. For example, they used the internet to recruit more than 1000 individuals who completed a questionnaire about schizophrenia-like experiences. Those prone to such experiences were more likely to have an inactive variant of a neurotransmitter gene. This is a new approach to unravelling the role of genes in mental illness.

Biography

Professor Bill Deakin graduated in Medicine at Leeds University in 1973. He took an extra year in his training to obtain a 1st in Physiology and this excited his interest in neurobiology and the organisation of behaviour. He specialised in Psychiatry and joined the Clinical Research Centre at Northwick Park, London to further his training and worked on his PhD at the National Institute for Medical Research, Mill Hill. He was a MRC Training Fellow for 5 years. His PhD investigated how distinct 5HT (serotonin) neurone pathways in the rat brain have different functions in regulating adaptive, coping responses to stress.

Bill moved to the University of Manchester as Senior Lecturer in the early 1980s to continue 5HT research but in clinical experimental medicine with volunteers and patients with depression, anxiety and antisocial behaviour. One study funded by the Wellcome Trust involved measuring stress hormones in saliva from 500 mothers in the Wythenshawe estate and relating hormone levels to psycho-social adversity and brain 5HT functioning. Some 5HT pathways appear to be involved in anxiety and work to keep us out of risky or stressful situations while others are concerned with resilience in the face of long-term difficulties. 5HT also has important roles in addiction and social behaviour.

Bill’s group developed ideas about the role of glutamate in schizophrenia at first from studies in human post-mortem brain. More recently they have developed novel magnetic resonance imaging methods to track the action of drugs in the brain such as the glutamate antagonist ketamine. Bill is currently investigating how the antibiotic minocycline appears to improve the outcome of treatment for schizophrenia.

He is the experimental medicine lead of the UK Mental Health Research Network, a National Institute for Health Research Senior Investigator and a Fellow of the Academy of Medical Sciences. He has over 200 refereed publications and an H-factor of 60.
 

Publications

2099

2016

  • Gonda, X., Eszlari, N., Kovacs, D., Anderson, I. M., Deakin, J. F. W., Juhasz, G., & Bagdy, G. (2016). Financial difficulties but not other types of recent negative life events show strong interactions with 5-HTTLPR genotype in the development of depressive symptoms. Translational Psychiatry, 6, e798. DOI:10.1038/tp.2016.57. Publication link: 4ba3b962-ab77-486d-8406-1372dbb2f90d | PubMed:27138797

2015

  • Chaudhry, I., Husain, N., Ur Rahman, R., Husain, M. O., Hamirani, M. M., Kazmi, A., ... Deakin, B. (2015). A randomised double-blind placebo-controlled 12- week feasibility trial of methotrexate added to treatment as usual in early schizophrenia: study protocol for a randomised controlled trial.Trials, 16(1), 1-9. [25563714]. DOI:10.1186-1745-6215-16-9, 10.1186/1745-6215-16-9. Publication link: 658ec318-8262-4208-b328-3b392238c398 | PubMed:25563714
  • Deakin, J. F. W., Dutta, A., & McKie, S. (2015). Ketamine and other potential glutamate antidepressants. Psychiatry Research, 225, 1-13. . Publication link: 44282264-9031-44a6-8c40-226026173c13
  • Hasan, A., Falkai, P., Wobrock, T., Glenthøj, B., Gattaz, W. F., Thibaut, F., ... Yamawaki, S. (2015). World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia. Part 3: Update 2015 Management of special circumstances: Depression, Suicidality, substance use disorders and pregnancy and lactation.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 16(3). DOI:10.3109/15622975.2015.1009163. Publication link: 8dbc5771-1ea7-46b7-866f-64d5b9fae467 | PubMed:25822804
  • Husain, M. I., Chaudhry, I. B., Rahman, R. R., Hamirani, M. M., Qurashi, I., Khoso, A. B., ... Young, A. H. (2015). Minocycline as an adjunct for treatment-resistant depressive symptoms: study protocol for a pilot randomised controlled trial.Trials, 16. DOI:10.1186/s13063-015-0933-5. Publication link: da937819-2e63-4fd0-8422-f059aa53ae13 | PubMed:26374703
  • Juhasz, G., Gonda, X., Hullam, G., Eszlari, N., Kovacs, D., Lazary, J., ... Bagdy, G. (2015). Variability in the effect of 5-HTTLPR on depression in a large European population: the role of age, symptom profile, type and intensity of life stressors.PLoS ONE, 10(3). DOI:10.1371/journal.pone.0116316. Publication link: 3b969e2b-d35c-4d69-bb83-9bf75eb20e0b | PubMed:25747798
  • Lisiecka, D. M., Suckling, J., Barnes, T. R. E., Chaudhry, I. B., Dazzan, P., Husain, N., ... Deakin, B. (2015). The benefit of minocycline on negative symptoms in early-phase psychosis in addition to standard care - extent and mechanism (BeneMin): study protocol for a randomised controlled trial.Trials, 16. DOI:10.1186/s13063-015-0580-x. Publication link: 03fda42b-e55e-4dcd-b6b4-9d91becb77f6 | PubMed:25886254
  • Lythe, K. E., Moll, J., Gethin, J. A., Workman, C. I., Green, S., Lambon Ralph, M. A., ... Zahn, R. (2015). Self-blame-Selective Hyperconnectivity Between Anterior Temporal and Subgenual Cortices and Prediction of Recurrent Depressive Episodes.JAMA psychiatry, 72(11). DOI:10.1001/jamapsychiatry.2015.1813. Publication link: 181c5163-32a2-45db-8e77-40754cf5bb36 | PubMed:26445229
  • Montejo, A. L., Deakin, J. F. W., Gaillard, R., Harmer, C., Meyniel, F., Jabourian, A., ... Goodwin, G. (2015). Better sexual acceptability of agomelatine (25 and 50 mg) compared to escitalopram (20 mg) in healthy volunteers. A 9-week, placebo-controlled study using the PRSexDQ scale.Journal of psychopharmacology (Oxford, England), 29(10). DOI:10.1177/0269881115599385. Publication link: 88851318-a8b5-495b-a400-2dc472d44804 | PubMed:26268533
  • Paterson, L. M., Flechais, R. S., Murphy, A., Reed, L. J., Abbott, S., Boyapati, V., ... Rabiner, I. (2015). The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description.Journal of psychopharmacology (Oxford, England), 29(9), 943-60. DOI:10.1177/0269881115596155. Publication link: ff02330f-657a-4995-821a-98d2384f132a | PubMed:26246443
  • Pulcu, E., Thomas, E. J., Trotter, P. D., McFarquhar, M., Juhasz, G., Sahakian, B. J., ... Haggis, B. (2015). Social-economical decision making in current and remitted major depression.Psychological Medicine, 45(6). DOI:10.1017/S0033291714002414. Publication link: 5ce980ee-2b8a-45f6-bc6e-4545daecb3f5 | PubMed:25300570
  • Sato, J. R., Moll, J., Green, S., Deakin, J. F. W., Thomaz, C. E., & Zahn, R. (2015). Machine learning algorithm accurately detects fMRI signature of vulnerability to major depression.Psychiatry research. DOI:10.1016/j.pscychresns.2015.07.001. Publication link: 8c993c1e-c3c0-462a-bfcd-2768cc6031a1 | PubMed:26187550
  • Zahn, R., Lythe, K. E., Gethin, J. A., Green, S., Deakin, J. F. W., Workman, C., & Moll, J. (2015). Negative emotions towards others are diminished in remitted major depression.European psychiatry : the journal of the Association of European Psychiatrists, 30(4). DOI:10.1016/j.eurpsy.2015.02.005. Publication link: 91e624bd-68b8-4b63-9348-6c28b7f16e6e | PubMed:25752724
  • Zahn, R., Lythe, K. E., Gethin, J. A., Green, S., Deakin, J. F. W., Young, A. H., & Moll, J. (2015). The role of self-blame and worthlessness in the psychopathology of major depressive disorder.Journal of affective disorders, 186. DOI:10.1016/j.jad.2015.08.001. Publication link: 58a4ba06-22af-4587-bf8b-d9a64621496d | PubMed:26277271

2014

  • Deakin, J. F. W., & Faulkner, P. (2014). The role of serotonin in reward, punishment and behavioural inhibition in humans: Insights from studies with acute tryptophan depletion. Neuroscience & Biobehavioral Reviews, 46, 365-378. . Publication link: b2e7f79d-c7f2-4acb-a444-c7aa9732edcc
  • Dutta, A., McKie, S., Deakin, J. F. W., & Haggis, B. (2014). Resting state networks in major depressive disorder.Psychiatry research, 224(3). DOI:10.1016/j.pscychresns.2014.10.003. Publication link: 40f7de1b-ae85-4b6f-81c8-d912dd82f562 | PubMed:25456520
  • Haggis, B., Juhasz, G., Hullam, G., Eszlari, N., Gonda, X., Antal, P., ... Bagdy, G. (2014). Brain galanin system genes interact with life stresses in depression-related phenotypes.Proceedings of the National Academy of Sciences of the United States of America, 111(16). DOI:10.1073/pnas.1403649111. Publication link: 2c0e7af0-1c70-48ad-8c12-f03a0f0a4ced | PubMed:24706871
  • Haggis, B., Pulcu, E., Lythe, K., Elliott, R., Green, S., Moll, J., ... Zahn, R. (2014). Increased amygdala response to shame in remitted major depressive disorder.PLoS ONE, 9(1). DOI:10.1371/journal.pone.0086900. Publication link: a4908c18-e85f-42bf-8a56-225383941444 | PubMed:24497992
  • Husain, N., CHAUDHRY, I. B., HUSAIN, N., DRAKE, R., DUNN, G., HUSAIN, M. O., ... DEAKIN, W. J. (2014). Add-on clinical effects of simvastatin and ondansetron in patients with schizophrenia stabilized on antipsychotic treatment: pilot study.Therapeutic Advances in Psychopharmacology, 4(3), 110-116. [25057343]. DOI:10.1177/2045125313511487. Publication link: b0dd5fed-53b2-4281-9929-0a4f56839b7b | PubMed:25057343
  • Mckie, S., McFarquhar, M., Elliott, R., McKie, S., Thomas, E., Downey, D., ... Haggis, B. (2014). TOMM40 rs2075650 may represent a new candidate gene for vulnerability to major depressive disorder. Neuropsychopharmacology, 39(7), 1743-1753. DOI:10.1038/npp.2014.22. Publication link: c4856c6e-dfdf-4c5a-bc23-f3704ee6f545 | PubMed:24549102
  • Pulcu, E., Trotter, P. D., Thomas, E. J., McFarquhar, M., Juhasz, G., Sahakian, B. J., ... Haggis, B. (2014). Temporal discounting in major depressive disorder.Psychological Medicine, 44(9), 1825-1834. DOI:10.1017/S0033291713002584. Publication link: acc7b092-d069-4b83-8a57-0194ae958bae | PubMed:24176142
  • Pulcu, E., Zahn, R., Moll, J., Trotter, P. D., Thomas, E. J., Juhasz, G., ... Haggis, B. (2014). Enhanced subgenual cingulate response to altruistic decisions in remitted major depressive disorder.NeuroImage. Clinical, 4. DOI:10.1016/j.nicl.2014.04.010. Publication link: e7e25c87-9eaf-45d6-a66c-15c44ec41ab9 | PubMed:24936421
  • Sarginson, J. E., Deakin, J. F. W., Anderson, I. M., Downey, D., Thomas, E., Elliott, R., ... Haggis, B. (2014). Neuronal nitric oxide synthase (NOS1) polymorphisms interact with financial hardship to affect depression risk.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(12). DOI:10.1038/npp.2014.137. Publication link: 9542b415-b99c-4340-8420-6770ba1c1be4 | PubMed:24917196

2013

  • Arnone, D., Mckie, S., Elliott, R., Juhasz, G., Thomas, E. J., Downey, D., ... Haggis, B. (2013). State-dependent changes in hippocampal grey matter in depression. Molecular Psychiatry, 18(12), 1265-1272. DOI:10.1038/mp.2012.150. Publication link: 6744dc1c-220b-4ab2-b426-150389699a9e | PubMed:23128153
  • Chaudhry, I. B., Husain, N., Husain, M. O., Hallak, J., Drake, R., Kazmi, A., ... Haggis, B. (2013). Ondansetron and simvastatin added to treatment as usual in patients with schizophrenia: study protocol for a randomized controlled trial.Trials, 14, 101. DOI:10.1186/1745-6215-14-101. Publication link: 4c9b9e3b-68ac-42e1-9023-76439f005e60 | PubMed:23782463
  • Deakin, J. (2013). The origins of '5-HT and mechanisms of defence' by Deakin and Graeff: a personal perspective.Journal of psychopharmacology (Oxford, England), 27(12). DOI:10.1177/0269881113503508. Publication link: c5a70f26-ce9f-4744-81c4-fbc21914bc78 | PubMed:24067790
  • Green, S., Lambon Ralph, M. A., Moll, J., Zakrzewski, J., Deakin, J. F. W., Grafman, J., ... Haggis, B. (2013). The neural basis of conceptual-emotional integration and its role in major depressive disorder. Social Neuroscience, 8(5), 417-433. DOI:10.1080/17470919.2013.810171. Publication link: a8611266-05f7-4b7b-8e54-9b13e380d742 | PubMed:23826933
  • Hasan, A., Falkai, P., Wobrock, T., Glenthoj, B., Gattaz, W. F., Thibaut, F., ... Haggis, B. (2013). World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia, part 2: update 2012 on the long-term treatment of schizophrenia and management of antipsychotic-induced side effects.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 14(1). DOI:10.3109/15622975.2012.739708. Publication link: 19dd83e2-fbcd-4096-aa38-04e8fc788369 | PubMed:23216388
  • Juhasz, G., Culverhouse, R. C., Bowes, L., Breslau, N., Nurnberger, J. I., Burmeister, M., ... Zucker, R. A. (2013). Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression. BMC Psychiatry, 13, [304]. DOI:10.1186/1471-244X-13-304. Publication link: bed28caa-11cd-4c25-8ab1-19e9c4aa49b6 | PubMed:24219410
  • Schmechtig, A., Lees, J., Grayson, L., Craig, K. J., Dadhiwala, R., Dawson, G. R., ... Haggis, B. (2013). Effects of risperidone, amisulpride and nicotine on eye movement control and their modulation by schizotypy.Psychopharmacology, 227(2). DOI:10.1007/s00213-013-2973-4. Publication link: 84f5a798-f596-4982-a57c-c9f880d79154 | PubMed:23430159

2012

  • Arnone, D., McKie, S., Elliott, R., Thomas, E. J., Downey, D., Juhasz, G., ... Haggis, B. (2012). Increased amygdala responses to sad but not fearful faces in major depression: relation to mood state and pharmacological treatment.The American journal of psychiatry, 169(8), 841-850. DOI:10.1176/appi.ajp.2012.11121774. Publication link: 9bc1b2ef-cb00-4f34-84a5-db31a8a6eb6b | PubMed:22854930
  • Chaudhry, I. B., Hallak, J., Husain, N., Minhas, F., Stirling, J., Richardson, P., ... Haggis, B. (2012). Minocycline benefits negative symptoms in early schizophrenia: A randomised double-blind placebo-controlled clinical trial in patients on standard treatment. Journal of Psychopharmacology, 26(9), 1185-1193. DOI:10.1177/0269881112444941. Publication link: 9d84da78-3d37-4184-82da-22ac52866696 | PubMed:22526685
  • Deakin, B., Symonds, C. S., McKie, S., Elliott, R., William Deakin, J. F., & Anderson, I. M. (2012). Detection of the acute effects of hydrocortisone in the hippocampus using pharmacological fMRI.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 22(12), 867-874. DOI:10.1016/j.euroneuro.2012.03.008. Publication link: 36e9a820-5660-416a-a193-a4bc278b0272 | PubMed:22521875
  • Fallon, P., Dursun, S., & Deakin, B. (2012). Drug-induced supersensitivity psychosis revisited: characteristics of relapse in treatment-compliant patients.Therapeutic advances in psychopharmacology, 2(1). DOI:10.1177/2045125311431105. Publication link: a8f04299-c43c-4017-8579-ca748cfef5b3 | PubMed:23983951
  • Goulden, N., Elliott, R., Suckling, J., Williams, S. R., Deakin, J. F. W., McKie, S., & Haggis, B. (2012). Sample Size Estimation for Comparing Parameters using DCM.Brain connectivity, 2(2), 80-90. DOI:10.1089/brain.2011.0057. Publication link: f544705d-d44f-4339-a836-807c6ca698c0 | PubMed:22559836
  • Goulden, N., McKie, S., Thomas, E. J., Downey, D., Juhasz, G., Williams, S. R., ... Haggis, B. (2012). Reversed frontotemporal connectivity during emotional face processing in remitted depression. Biological Psychiatry, 72(7), 604-611. DOI:10.1016/j.biopsych.2012.04.031. Publication link: ca30b203-ba0e-44e1-9d73-d990b0c2f673 | PubMed:22682158
  • Green, S., Moll, J., Deakin, J. F. W., Hulleman, J., Zahn, R., & Haggis, B. (2012). Proneness to decreased negative emotions in major depressive disorder when blaming others rather than oneself. Psychopathology, 46(1), 34-44. DOI:10.1159/000338632. Publication link: bc464a2f-d783-43fd-b546-f8a092357daa | PubMed:22890331
  • Haggis, B., Elliott, R., Lythe, K., Lee, R., McKie, S., Juhasz, G., ... Anderson, I. M. (2012). Reduced medial prefrontal responses to social interaction images in remitted depression.Archives of General Psychiatry, 69(1), 37-45. DOI:10.1001/archgenpsychiatry.2011.139. Publication link: 441c51b7-f44f-4379-a222-201e6f20a549 | PubMed:22213787
  • Haggis, B., Green, S., Lambon Ralph, M. A., Moll, J., Deakin, J. F. W., & Zahn, R. (2012). Guilt-selective functional disconnection of anterior temporal and subgenual cortices in major depressive disorder.Archives of General Psychiatry, 69(10), 1014-1021. DOI:10.1001/archgenpsychiatry.2012.135. Publication link: 5e929998-687b-430a-a33e-ef64dd81943b | PubMed:22638494
  • Haggis, B., Hasan, A., Falkai, P., Wobrock, T., Glenthoj, B., Gattaz, W. F., ... Yamawaki, S. (2012). World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, part 1: update 2012 on the acute treatment of schizophrenia and the management of treatment resistance.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 13(5). DOI:10.3109/15622975.2012.696143. Publication link: 29e8be31-8d28-465e-83c6-b20206f1cef7 | PubMed:22834451
  • Haggis, B., Millan, M. J., Agid, Y., Brüne, M., Bullmore, E. T., Carter, C. S., ... Young, L. J. (2012). Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy.Nature reviews. Drug discovery, 11(2). DOI:10.1038/nrd3628. Publication link: 56cbca41-010d-4258-831a-07d98e7ec299 | PubMed:22293568
  • Hodkinson, D. J., de Groote, C., McKie, S., Deakin, J. F. W., & Williams, S. R. (2012). Differential Effects of Anaesthesia on the phMRI Response to Acute Ketamine Challenge.British journal of medicine and medical research, 2(3). . Publication link: 4c6cfdbe-1c91-4584-a892-6afa0972100d | PubMed:22737655
  • Koychev, I., El-Deredy, W., Mukherjee, T., Haenschel, C., Deakin, J. F. W., & Haggis, B. (2012). Core dysfunction in schizophrenia: electrophysiology trait biomarkers.Acta Psychiatrica Scandinavica, 126(1), 59-71. DOI:10.1111/j.1600-0447.2012.01849.x. Publication link: 22d6e9b0-4258-4e0f-b5d2-720e1bcd28ad | PubMed:22384856
  • Koychev, I., McMullen, K., Lees, J., Dadhiwala, R., Grayson, L., Perry, C., ... Haggis, B. (2012). A validation of cognitive biomarkers for the early identification of cognitive enhancing agents in schizotypy: a three-center double-blind placebo-controlled study.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 22(7). DOI:10.1016/j.euroneuro.2011.10.005. Publication link: 48177ca2-844a-4382-92fc-ead361ce505e | PubMed:22137565
  • Mckie, S., Suckling, J., Barnes, A., Job, D., Brennan, D., Lymer, K., ... Williams, S. (2012). The neuro/PsyGRID calibration experiment: Identifying sources of variance and bias in multicenter MRI studies. Human Brain Mapping, 33(2), 373-386. DOI:10.1002/hbm.21210. Publication link: cc72c147-e5fc-46df-bd77-0a072a3e559b | PubMed:21425392
  • Pap, D., Gonda, X., Molnar, E., Lazary, J., Benko, A., Downey, D., ... Haggis, B. (2012). Genetic variants in the catechol-o-methyltransferase gene are associated with impulsivity and executive function: Relevance for major depression. American Journal of Medical Genetics - Neuropsychiatric Genetics, 159(8), 928-940. DOI:10.1002/ajmg.b.32098. Publication link: 2312ff2a-d965-4930-b518-89a8a83ef3e9 | PubMed:23008195

2011

2010

  • Alves-Neto, W. C., Guapo, V. G., Graeff, F. G., Deakin, J. F. W., & Del-Ben, C. M. (2010). Effect of escitalopram on the processing of emotional faces. Brazilian Journal of Medical and Biological Research, 43(3), 285-289. DOI:10.1590/S0100-879X2010005000007. Publication link: ba00a6f9-4139-4789-a3d0-9bb4b8b12f86 | PubMed:20209375
  • Benko, A., Lazary, J., Molnar, E., Gonda, X., Tothfalusi, L., Pap, D., ... Bagdy, G. (2010). Significant association between the C[-1019]G functional polymorphism of the HTR1A gene and impulsivity. American Journal of Medical Genetics - Neuropsychiatric Genetics, 153(2), 592-599. DOI:10.1002/ajmg.b.31025. Publication link: 50819eeb-1fe0-4e1a-8c35-99472813e151 | PubMed:19725031
  • da Costa Araújo, S., Body, S., Torres, L. V. V., Sanchez, C. M. O., Bak, V. K., Deakin, J. F. W., ... Szabadi, E. (2010). Choice between reinforcer delays versus choice between reinforcer magnitudes: Differential Fos expression in the orbital prefrontal cortex and nucleus accumbens core. Behavioural Brain Research, 213(2), 269-277. DOI:10.1016/j.bbr.2010.05.014. Publication link: 2322ebbd-e241-4de2-a313-bbea523d48bf | PubMed:20570596
  • Elliott, R., Agnew, Z., & Deakin, J. F. W. (2010). Hedonic and informational functions of the human orbitofrontal cortex. Cerebral Cortex, 20(1), 198-204. DOI:10.1093/cercor/bhp092. Publication link: 0b073ac2-a5bb-437e-89c0-4bce63682577 | PubMed:19435707
  • Goulden, N., McKie, S., Suckling, J., Williams, S. R., Anderson, I. M., William Deakin, J. F., & Elliott, R. (2010). A comparison of permutation and parametric testing for between group effective connectivity differences using DCM. NeuroImage, 50(2), 509-515. DOI:10.1016/j.neuroimage.2009.11.059. Publication link: fac3f8a6-7dd6-4108-9741-6b1adfe35a27 | PubMed:20004253
  • Juhasz, G., Downey, D., Hinvest, N., Thomas, E., Chase, D., Toth, Z. G., ... Anderson, I. M. (2010). Risk-taking behavior in a gambling task associated with variations in the tryptophan hydroxylase 2 gene: relevance to psychiatric disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 35(5), 1109-1119. DOI:10.1038/npp.2009.216. Publication link: 6a82ae18-b636-4328-b16b-4a57c2f50597 | PubMed:20043001
  • Koychev, I., El-Deredy, W., Haenschel, C., & Deakin, J. F. W. (2010). Visual information processing deficits as biomarkers of vulnerability to schizophrenia: An event-related potential study in schizotypy. Neuropsychologia, 48(7), 2205-2214. DOI:10.1016/j.neuropsychologia.2010.04.014. Publication link: 05bd37de-21e9-4207-ad53-97d34959c34b | PubMed:20412812
  • Mckie, S., Kong, Y., Mukherjee, T., McKie, S., Deakin, J. F. W., & Williams, S. (2010). Analysis of connectivity in the resting state of the default mode of brain function: A major role for the cerebellum?. International Journal of Modelling, Identification and Control, 9(3), 236-246. DOI:10.1504/IJMIC.2010.032804. Publication link: 056983b3-250f-4337-a400-ff0cde9f299f
  • Mckie, S., Völlm, B., Richardson, P., McKie, S., Reniers, R., Elliott, R., ... Vollm, B. (2010). Neuronal correlates and serotonergic modulation of behavioural inhibition and reward in healthy and antisocial individuals. Journal of Psychiatric Research, 44(3), 123-131. DOI:10.1016/j.jpsychires.2009.07.005. Publication link: 07c2a406-99bd-43d7-a1a1-3d2bf7f3975a | PubMed:19683258
  • Williams, S., Suckling, J., Barnes, A., Job, D., Brenan, D., Lymer, K., ... Deakin, B. (2010). Power calculations for multicenter imaging studies controlled by the false discovery rate. Human Brain Mapping, 31(8), 1183-1195. DOI:10.1002/hbm.20927. Publication link: d493a70c-9ecc-4406-870e-f516e248c3b5

2009

  • Bezzina, G., Cheung, T. H. C., Body, S., Deakin, J. F. W., Anderson, I. M., Bradshaw, C. M., & Szabadi, E. (2009). Quantitative analysis of the effect of lesions of the subthalamic nucleus on intertemporal choice: Further evidence for enhancement of the incentive value of food reinforcers. Behavioural Pharmacology, 20(5-6), 437-446. DOI:10.1097/FBP.0b013e3283305e4d. Publication link: f460cc79-19b8-435a-91d5-dd192fcad82f | PubMed:19667971
  • da Costa Araújo, S., Body, S., Hampson, C. L., Langley, R. W., Deakin, J. F. W., Anderson, I. M., ... Szabadi, E. (2009). Effects of lesions of the nucleus accumbens core on inter-temporal choice: Further observations with an adjusting-delay procedure. Behavioural Brain Research, 202(2), 272-277. DOI:10.1016/j.bbr.2009.04.003. Publication link: f2f078d5-33d7-43e5-b95f-52004a70201f | PubMed:19463712
  • Dunham, J. S., Deakin, J. F. W., Miyajima, F., Payton, A., & Toro, C. T. (2009). Expression of hippocampal brain-derived neurotrophic factor and its receptors in Stanley consortium brains. Journal of Psychiatric Research, 43(14), 1175-1184. DOI:10.1016/j.jpsychires.2009.03.008. Publication link: 3a184596-c18c-4d54-92a9-0bc20c8504e9 | PubMed:19376528
  • Juhasz, G., Chase, D., Pegg, E., Downey, D., Toth, Z. G., Stones, K., ... Deakin, J. F. W. (2009). CNR1 gene is associated with high neuroticism and low agreeableness and interacts with recent negative life events to predict current depressive symptoms.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 34(8), 2019-2027. DOI:10.1038/npp.2009.19. Publication link: 70e44a4c-c006-42e2-ad32-d02958505944 | PubMed:19242408
  • Juhasz, G., Lazary, J., Chase, D., Pegg, E., Downey, D., Toth, Z. G., ... Bagdy, G. (2009). Variations in the cannabinoid receptor 1 gene predispose to migraine. Neuroscience Letters, 461(2), 116-120. DOI:10.1016/j.neulet.2009.06.021. Publication link: 7dbdf8b6-9faa-4168-924e-5ffa223fcf34 | PubMed:19539700
  • Kleyn, C. E., McKie, S., Ross, A. R., Montaldi, D., Gregory, L. J., Elliott, R., ... Griffiths, C. E. M. (2009). Diminished neural and cognitive responses to facial expressions of disgust in patients with psoriasis: A functional magnetic resonance imaging study. Journal of Investigative Dermatology, 129(11), 2613-2619. DOI:10.1038/jid.2009.152. Publication link: 2f743433-e9fd-405f-af1d-9b1134a8ff55 | PubMed:19710691
  • Kong, Y., Mukherjee, T. T., Deakin, J. F. W., Williams, S. R., & McKie, S. (2009). Analysis of connectivity in the resting state of the default-mode of brain function: a major role for the cerebellum?. International Journal of Modelling, Identification and Control, 9(3), 236-246. . Publication link: e080daaf-ae30-46bc-9b61-ff41d2866b56
  • Völlm, B. A., Zhao, L., Richardson, P., Clark, L., Deakin, J. F. W., Williams, S., & Dolan, M. C. (2009). A voxel-based morphometric MRI study in men with borderline personality disorder: Preliminary findings. Criminal Behaviour and Mental Health, 19(1), 64-72. DOI:10.1002/cbm.716. Publication link: 2ac1491f-8d60-430f-ad58-bf413bed1e3a | PubMed:19172640
  • Deakin, J. F. W. (2009). Brain sciences addiction and drugs; chapter 7 medicines for mental health. London: No publisher name.. Publication link: b73353dd-b317-4c47-826f-d3e6d9c9b532

2008

  • Anderson, I. M., McKie, S., Elliott, R., Williams, S. R., & Deakin, J. F. W. (2008). Assessing human 5-HT function in vivo with pharmacoMRI. Neuropharmacology, 55(6), 1029-1037. DOI:10.1016/j.neuropharm.2008.06.029. Publication link: 99d80d33-cc4e-40e4-b3d3-53054f87d3a2 | PubMed:18621068
  • Bezzina, G., Body, S., Cheung, T. H. C., Hampson, C. L., Bradshaw, C. M., Szabadi, E., ... Deakin, J. F. W. (2008). Effect of disconnecting the orbital prefrontal cortex from the nucleus accumbens core on inter-temporal choice behaviour: A quantitative analysis. Behavioural Brain Research, 191(2), 272-279. DOI:10.1016/j.bbr.2008.03.041. Publication link: 5584b7d8-edfe-4d05-8361-4e6ba02cbc9b
  • Bezzina, G., Body, S., Cheung, T. H. C., Hampson, C. L., Deakin, J. F. W., Anderson, I. M., ... Bradshaw, C. M. (2008). Effect of quinolinic acid-induced lesions of the nucleus accumbens core on performance on a progressive ratio schedule of reinforcement: Implications for inter-temporal choice. Psychopharmacology, 197(2), 339-350. DOI:10.1007/s00213-007-1036-0. Publication link: 2438763c-838d-4e53-896c-543dcf3a1817
  • Bezzina, G., Boon, F. S. D., Hampson, C. L., Cheung, T. H. C., Body, S., Bradshaw, C. M., ... Deakin, J. F. W. (2008). Effect of quinolinic acid-induced lesions of the subthalamic nucleus on performance on a progressive-ratio schedule of reinforcement: A quantitative analysis. Behavioural Brain Research, 195(2), 223-230. DOI:10.1016/j.bbr.2008.09.005. Publication link: 6ad2df15-98cf-45d6-8dac-be82abfb85fe
  • Deakin, J. F. W., Lees, J., McKie, S., Hallak, J. E. C., Williams, S. R., & Dursun, S. M. (2008). Glutamate and the neural basis of the subjective effects of ketamine: A pharmaco-magnetic resonance imaging study. Archives of General Psychiatry, 65(2), 154-164. DOI:10.1001/archgenpsychiatry.2007.37. Publication link: e26c4639-af94-46b9-8e71-b1cf5b1a3666
  • Elliott, R., Agnew, Z., & Deakin, J. F. W. (2008). Medial orbitofrontal cortex codes relative rather than absolute value of financial rewards in humans. European Journal of Neuroscience, 27(9), 2213-2218. DOI:10.1111/j.1460-9568.2008.06202.x. Publication link: e7b61550-843d-4309-a846-3efb103b9d76 | PubMed:18445214
  • Lubman, D. I., Allen, N. B., Peters, L. A., & Deakin, J. F. W. (2008). Electrophysiological evidence that drug cues have greater salience than other affective stimuli in opiate addiction. Journal of Psychopharmacology, 22(8), 836-842. DOI:10.1177/0269881107083846. Publication link: 4e119d2c-55e7-4918-a7ef-eb3dc98cffbf
  • Oliveira, R. M. W., Guimarães, F. S., & Deakin, J. F. W. (2008). Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders. Brazilian Journal of Medical and Biological Research, 41(4), 333-341. . Publication link: 0b01af71-507f-42a7-945b-6ab72f6a48b7

2007

  • Anderson, I. M., Del-Ben, C. M., McKie, S., Richardson, P., Williams, S. R., Elliott, R., & William Deakin, J. F. (2007). Citalopram modulation of neuronal responses to aversive face emotions: A functional MRI study. NeuroReport, 18(13), 1351-1355. DOI:10.1097/WNR.0b013e3282742115. Publication link: a85a9975-ef15-4ee8-b48f-f7c4be74c611 | PubMed:17762711
  • Hallak, J. E. C., Crippa, J. A. D. S., Pinto, J. P., De Sousa, J. P. M., Trzesniak, C., Dursun, S. M., ... Zuardi, A. W. (2007). Total agenesis of the corpus callosum in a patient with childhood-onset schizophrenia. Arquivos de Neuro-Psiquiatria, 65(4 B), 1216-1219. DOI:10.1590/S0004-282X2007000700024. Publication link: c2f8300c-08a3-42bf-9d5d-98429e6c701a
  • Lubman, D. I., Allen, N. B., Peters, L. A., & Deakin, J. F. W. (2007). Electrophysiological evidence of the motivational salience of drug cues in opiate addiction. Psychological Medicine, 37(8), 1203-1209. DOI:10.1017/S0033291707009932. Publication link: e95b25b7-cc90-4fc9-b2a1-67fbdfbf21c2
  • Toro, C. T., & Deakin, J. F. W. (2007). Adult neurogenesis and schizophrenia: A window on abnormal early brain development?. Schizophrenia Research, 90(1-3), 1-14. DOI:10.1016/j.schres.2006.09.030. Publication link: fd717e72-35b9-46d1-aeaf-25169f942fa9
  • Toro, C. T., Hallak, J. E., Dunham, J. S., Leite, J. P., Sakamoto, A. C., Guarnieri, R., ... Deakin, J. F. W. (2007). The NR1 N-methyl-D-aspartate subunit and brain-derived neurotrophic factor in temporal lobe epilepsy hippocampus: A comparison of patients with and without coexisting psychiatric symptoms. Epilepsia, 48(12), 2352-2356. DOI:10.1111/j.1528-1167.2007.01194.x. Publication link: 6b8a837f-3dee-4409-a050-1af9474c1463
  • Völlm, B., Richardson, P., McKie, S., Elliott, R., Dolan, M., Deakin, B., & Vollm, B. (2007). Neuronal correlates of reward and loss in Cluster B personality disorders: A functional magnetic resonance imaging study. Psychiatry Research - Neuroimaging, 156(2), 151-167. DOI:10.1016/j.pscychresns.2007.04.008. Publication link: 8c90446c-e003-4c26-9422-7586b2ebe7d8 | PubMed:17920821

2006

  • Richardson, P. C., Deakin, J. F. W., Elliott, R., Vollm, B. A., Drury, A., & McKie, S. (2006). Cooperation with another player in a financially rewarded guessing game activates regions implicated in theory of mind. Social Neuroscience, 1. . Publication link: 7e4af59a-c671-4f95-b205-6b0e8a9998b1
  • Toro, C. T., Hallak, J. E. C., Dunham, J. S., & Deakin, J. F. W. (2006). Glial fibrillary acidic protein and glutamine synthetase in subregions of prefrontal cortex in schizophrenia and mood disorder. Neuroscience Letters, 404(3), 276-281. DOI:10.1016/j.neulet.2006.05.067. Publication link: ca25272c-92e0-40ed-aa5d-0db0aed723c4
  • Vollm, B., Mckie, S., Völlm, B. A., Taylor, A. N. W., Richardson, P., Corcoran, R., ... Elliott, R. (2006). Neuronal correlates of theory of mind and empathy: A functional magnetic resonance imaging study in a nonverbal task. NeuroImage, 29(1), 90-98. DOI:10.1016/j.neuroimage.2005.07.022. Publication link: 53e89b1e-51f5-45df-a672-c1ad0ceec18b
  • Völlm, B., Richardson, P., McKie, S., Elliott, R., Deakin, J. F. W., Anderson, I. M., & Vollm, B. (2006). Serotonergic modulation of neuronal responses to behavioural inhibition and reinforcing stimuli: An fMRI study in healthy volunteers. European Journal of Neuroscience, 23(2), 552-560. DOI:10.1111/j.1460-9568.2005.04571.x. Publication link: f6d361bc-8aac-4ef7-9a1c-ea6598c8100b

2005

  • Deakin, J. F. W., & Elliott, R. (2005). Role of the Orbitofrontal Cortex in Reinforcement Processing and Inhibitory Control: Evidence from FMRI Studies in Healthy Human Subjects.International Review of Neurobiology. . Publication link: f4dd4a2b-eba5-413a-915a-379c248571a6
  • Diaz, P., Bhaskara, S., Dursun, S. M., & Deakin, B. (2005). Double-blind, placebo-controlled, crossover trial of clozapine plus glycine in refractory schizophrenia negative results [2]. Journal of Clinical Psychopharmacology, 25(3), 277-278. DOI:10.1097/01.jcp.0000165740.22377.6d. Publication link: 2e1be976-0a43-423f-a203-627bfb6bf81c
  • Dursun, S. M., Hallak, J. E. C., Haddad, P., Leahy, A., Byrne, A., Strickland, P. L., ... Deakin, J. F. W. (2005). Clozapine monotherapy for catatonic schizophrenia: Should clozapine be the treatment of choice, with catatonia rather than psychosis as the main therapeutic index? [2]. Journal of Psychopharmacology, 19(4), 432-433. DOI:10.1177/0269881105053313. Publication link: 969d4c25-0a27-4933-a3fd-c221b9bef721
  • Ersche, K. D., Fletcher, P. C., Lewis, S. J. G., Clark, L., Stocks-Gee, G., London, M., ... Sahakian, B. J. (2005). Abnormal frontal activations related to decision-making in current and former amphetamine and opiate dependent individuals. Psychopharmacology, 180(4), 612-623. DOI:10.1007/s00213-005-2205-7. Publication link: c09dcf29-169b-48b3-b72d-254d98a239cc | PubMed:16163533
  • Guarnieri, R., Wichert-Ana, L., Hallak, J. E. C., Velasco, T. R., Walz, R., Kato, M., ... Sakamoto, A. C. (2005). Interictal SPECT in patients with mesial temporal lobe epilepsy and psychosis: A case-control study. Psychiatry Research - Neuroimaging, 138(1), 75-84. DOI:10.1016/j.pscychresns.2004.10.003. Publication link: f72a2372-c2e2-4260-94a2-2f8454b87b31
  • Kheramin, S., Body, S., Herrera, F. M., Bradshaw, C. M., Szabadi, E., Deakin, J. F. W., & Anderson, I. M. (2005). The effect of orbital prefrontal cortex lesions on performance on a progressive ratio schedule: Implications for models of inter-temporal choice. Behavioural Brain Research, 156(1), 145-152. DOI:10.1016/j.bbr.2004.05.017. Publication link: 25bc6fe9-65f8-445a-84df-a7121b151df8
  • Pickles, A., Kerfoot, M., Toro, C., Deakin, J. F. W., & Aglan, A. (2005). NMDA receptor subunit NRI and postsynaptic protein PSD-95 in hippocampus and orbitofrontal cortex in schizophrenia and mood disorder. Schizophrenia Research, 80(2-3), 323-330. DOI:10.1016/j.schres.2005.07.003. Publication link: a5f56ced-c7ad-4da0-baab-d2432718d7ff
  • Richell, R. A., Deakin, J. F. W., & Anderson, I. M. (2005). Effect of acute tryptophan depletion on the response to controllable and uncontrollable noise stress. Biological Psychiatry, 57(3), 295-300. DOI:10.1016/j.biopsych.2004.10.010. Publication link: c3675b3f-ad52-4d99-ac83-06a020c3348f

2004

  • Bantick, R. A., Montgomery, A. J., Bench, C. J., Choudhry, T., Malek, N., McKenna, P. J., ... Grasby, P. M. (2004). A positron emission tomography study of the 5-HT1A receptor in schizophrenia and during clozapine treatment. Journal of Psychopharmacology, 18(3), 346-354. DOI:10.1177/026988110401800304. Publication link: a2a79695-ab48-477f-952f-c1fc8e8d6551
  • Deakin, J. F. W., Elliott, R., Ranote, S., Abel, K., Mitchell, R., & Appleby, L. (2004). The neural basis of maternal responsiveness to infants: an fMRI study.Neuroreport, 15( 11). . Publication link: 806b78a6-cfb7-4731-a8e4-b06392ba9cbd
  • Elliott, R., Newman, J. L., Longe, O. A., & Deakin, J. F. W. (2004). Instrumental responding for rewards is associated with enhanced neuronal response in subcortical reward systems. NeuroImage, 21(3), 984-990. DOI:10.1016/j.neuroimage.2003.10.010. Publication link: b2d6d264-fefb-4089-a1db-4f57ace3ca90
  • Völlm, B., Richardson, P., Stirling, J., Elliott, R., Dolan, M., Chaudhry, I., ... Deakin, B. (2004). Neurobiological substrates of antisocial and borderline personality disorder: Preliminary results of a functional fMRI study. Criminal Behaviour and Mental Health, 14(1), 39-54. DOI:10.1002/cbm.559. Publication link: f86adfdd-67f9-476d-b769-9fe01618cf68

2003

  • Deakin, J. F. W. (2003). Depression and antisocial personality disorder: Two contrasting disorders of 5HT function. Journal of Neural Transmission, Supplementa, (64), 79-93. . Publication link: dcdbc910-993b-4110-bdfc-534660192acc
  • Elliott, R., Deakin, J. F. W., Newman, J. L., & Longe, O. A. (2003). Differential response patterns in the striatum and orbitofrontal cortex to financial reward in humans: a parametric fMRI study. Journal of Neuroscience, 23 (1). . Publication link: ae7055e4-91c5-47ff-a114-9cce5fe86995
  • Kheramin, S., Body, S., Ho, M. Y., Velázquez-Martinez, D. N., Bradshaw, C. M., Szabadi, E., ... Anderson, I. M. (2003). Role of the orbital prefrontal cortex in choice between delayed and uncertain reinforcers: A quantitative analysis. Behavioural Processes, 64(3), 239-250. DOI:10.1016/S0376-6357(03)00142-6. Publication link: 7a4e93fb-e880-4cb2-8142-eb43c0b24971
  • Strickland, P. L., John, S., Payton, A., Ollier, W., & Deakin, J. F. W. (2003). Do polymorphic genes influence prolactin responses to dexfenfluramine?. American Journal of Medical Genetics, 120A. . Publication link: e21ab289-16f4-47f1-abb3-09aa91a64925
  • Strickland, P. L., John, S., Payton, A., Worthington, J., Ollier, W. E. R., & Deakin, J. F. W. (2003). Do genetic polymorphisms of serotonin (5-HT) neurotransmission influence function in humans? [3]. American Journal of Medical Genetics, 120(4), 566-567. . Publication link: d2f504cd-579e-4a3b-9ced-542e3223c9c4

2002

  • Anderson, I. M., Clark, L., Elliott, R., Kulkarni, B., Williams, S. R., & Deakin, J. F. W. (2002). 5-HT2C receptor activation by m-chlorophenylpiperazine detected in humans with fMRI. NeuroReport, 13(12), 1547-1551. . Publication link: 3082987c-16c4-4fb1-8a59-cc87086c94bc
  • Anderson, I., Clark, L., Elliott, R., Kulkarni, B., Williams, S., & Deakin, J. F. W. (2002). 5-HT2C receptor activation detected in humans by fMRI.Neuroimage, 16(3). . Publication link: 13048492-6103-426a-9f63-fb432fc671ee
  • Chaudhry, I. B., Soni, S. D., Hellewell, J. S. E., & Deakin, J. F. W. (2002). Effects of the 5HT antagonist cyproheptadine on neuropsychological function in chronic schizophrenia. Schizophrenia Research, 53(1-2), 17-24. DOI:10.1016/S0920-9964(01)00165-7. Publication link: 131b25c8-7159-4283-a294-3d8005d2e935
  • Clark, L., Elliott, R., Deakin, J. F. W., & Anderson, I. (2002). Preference conditioning using supraliminal and subliminal monetary reinforcers in normal volunteers.Journal of Psychopharmacology, 16(3). . Publication link: a6ea42b6-c6e4-4ec3-a8bd-7a2d0f0dfd47
  • Deakin, J. F. W., Strickland, P. L., Rostron, E., Haddad, P., & Dursun, S. M. (2002). Assessment and management of "compulsive scratching" in schizophrenia with chronic renal failure. Canadian Journal of Psychiatry, 47 (5). . Publication link: cad4895b-4ae4-4047-a2f2-ac9feb4122a6
  • Deakin, J. F. W., Toro, C. T., & Law, A. J. (2002). Glutamate system gene expression in schizophrenia.European Psychiatry: the Journal of the Association of European Psychiatrists, 17(1). . Publication link: 6fbaf4a8-f42a-44aa-9b87-b382ec396340
  • Dolan, M., Dolan, M. C., Deakin, J. F. W., Roberts, N., & Anderson, I. M. (2002). Quantitative frontal and temporal structural MRI studies in personality-disordered offenders and control subjects. Psychiatry Research - Neuroimaging, 116(3), 133-149. DOI:10.1016/S0925-4927(02)00085-9. Publication link: 1b10bff3-4ace-4e08-a802-e60f8f5e00ec
  • Haddad, P. M., Strickland, P. L., Anderson, I., Deakin, J. F. W., & Dursun, S. M. (2002). Effects of MDMA (ecstasy) use and abstention on serotonin neurons. Lancet, 359. . Publication link: c97f9b50-a99f-40b5-91ab-eae103c75a0f
  • Morriss, R. K., Robson, M. J., & Deakin, W. J. (2002). Neuropsychological performance and noradrenaline function in chronic fatigue syndrome under conditions of high arousal. Psychopharmacology, 163(2), 166-173. DOI:10.1007/s00213-002-1129-8. Publication link: c8c6db42-2ba1-4485-ba42-e6291ef382cb
  • Strickland, P. L., Deakin, J. F. W., Percival, C., Dixon, J., Gater, R. A., & Goldberg, D. P. (2002). Bio-social origins of depression in the community: Interactions between social adversity, cortisol and serotonin neurotransmission. British Journal of Psychiatry, 180, 168-173. DOI:10.1192/bjp.180.2.168. Publication link: 372da820-61d3-4c36-9254-245416334406
  • Strickland, P., Rostron, E., Haddad, P., Deakin, J. F. W., & Dursun, S. M. (2002). Assessing and managing compulsive scratching in schizophrenia with chronic renal failure [2]. Canadian Journal of Psychiatry, 47(5), 484-485. . Publication link: b0559b59-6530-419f-9f8c-70a673a4b5e1
  • Tarrier, N., Sommerfield, C., Connell, J., Deakin, B., Pilgrim, H., & Reynolds, M. (2002). The psychophysiological responses of PTSD patients: Habituation, responses to stressful and neutral vignettes and association with treatment outcome. Behavioural and Cognitive Psychotherapy, 30(2), 129-142. DOI:10.1017/S1352465802002011. Publication link: 02300710-e6d1-4e44-b88f-93433fed62a9

2001

  • Deakin, J. F. W., & Law, A. J. (2001). Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses. NeuroReport, 12(13). . Publication link: 49da6ac9-44d6-4078-b9d3-794666d3ef6e
  • Deakin, J. F. W., Tarrier, N., Farrow, T. F. W., Zheng, Y., Wilkinson, I. D., Spence, S. A., ... Woodruff, P. W. R. (2001). Investigating the physiology of empathy and forgiveness: Towards a functional anatomy of understanding and reparation. NeuroReport, 12, 2433-3438. . Publication link: 5a4ebbbd-d8c3-4f3e-b85d-6f09828cb56b
  • Dolan, M., Anderson, I. M., & Deakin, J. F. W. (2001). Relationship between 5-HT function and impulsivity and aggression in male offenders with personality disorders. British Journal of Psychiatry, 178, 352-359. DOI:10.1192/bjp.178.4.352. Publication link: d07662b8-699c-4cf0-a238-1e9782201497
  • Farrow, T. F. D., Zheng, Y., Wilkinson, I. D., Spence, S. A., Deakin, J. F. W., Tarrier, N., ... Woodruff, P. W. R. (2001). Investigating the functional anatomy of empathy and forgiveness. NeuroReport, 12(11), 2433-2438. . Publication link: 9c6c9a91-2217-41d8-895c-be47355af35c

1998

Research projects